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Are you a patient needing assistance? Reach out via hello@rarediseases.co.za

for a

better 

tomorrow

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#1in15 South Africans are affected by rare diseases

That's the equivalent of 1 player in every rugby team! 

Whilst uniquely they may be rare, with more than 7000 known rare diseases, collectively they are more common than anticipated.

 

At Rare Diseases South Africa, we’re doing our best to support those 4.2 million South Africans who have been, or will be, diagnosed with a rare disease or congenital disorder in their lifetime. 

 

Our mission is to ensure a better tomorrow for all those impacted.

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the lives

 we touch

Rare Diseases South Africa is a registered non-profit organisation (NPO 120-991) advocating for a better tomorrow for the #1in15 South Africans impacted by rare diseases and congenital disorders,  including greater recognition, support, improved health service and better overall quality of life.

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community

become

part of our

Whether you're a patient, carer, family member, healthcare professional or even an athlete willing to use your mobility for the benefit of those without your voice counts and your input matters.

Get involved and help us to leave a legacy... a better tomorrow.

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giving is 
good medicine

Support Rare Diseases SA, in any way you are able to, and invest in a better tomorrow for the 1 in 15 South Africans that are, or who will be, impacted by a rare disease or congenital disorder at some point in their lives.

Rare Diseases South Africa is a registered Non-Profit Organisation (NPO 120-991) and relies on donations and contributions from the public to enable us to continue our work in advocacy and research.

Back the team who supports the #1in15.

upcoming events

  • #Swim4Sadie Midmar Mile 2026
    #Swim4Sadie Midmar Mile 2026
    Sat, 07 Feb
    aQuellé Midmar Mile
    07 Feb 2026, 00:00 – 08 Feb 2026, 12:00
    aQuellé Midmar Mile, Midmar Dam, Howick, 3290, South Africa
    Join us again at the aQuellé Midmar Mile on the weekend of 7-8 February, as part of #Swim4Sadie. Sadie’s life was heartbreakingly short. A rare disease took her before she could celebrate her fourth birthday. Yet her story continues to inspire action, compassion, and hope.
  • The Cape Town Cycle Tour - 2026
    The Cape Town Cycle Tour - 2026
    08 Mar 2026, 00:00 – 12:00
    Cape Town, Shop G13, Adderley St, Foreshore, Cape Town, 8001, South Africa
    Take on the iconic Cape Town Cycle Tour with purpose by joining #Ride4Rare. Experience breathtaking coastal views and the natural beauty of Cape Town’s world-famous route, all while using your passion and athletic ability to raise awareness and funds.
  • Swing for Independence Charity Golf Day
    Swing for Independence Charity Golf Day
    12 Jun 2026, 09:00 – 16:00
    Johannesburg, Illovo, Johannesburg, 2196, South Africa
    Join us for a day on the green that’s more than just golf — it’s about making a tangible difference in someone’s life. The Swing for Independence Charity Golf Day will raise vital funds to support Kerry Walsh, an SMA (Spinal Muscular Atrophy) warrior, motivational speaker, and disability advocate

let our stories inspire you

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our corporate members

be the first to know

RDSA will be reimplementing our monthly newsletters to update you on our work and the progress we're making within the rare disease and congenital disorder landscape in South Africa.

 

We have four newsletter which will contain unique information based on our four pillars: Community Engagement, Advocacy, Patient Navigation and Research.

Subscribe to our newsletters

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for a better tomorrow

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Physical Address

The Station, 63 Peter Place, Bryanston, Sandton, 2021

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NPO: 120-991 

NPC: 2016/071131/08 

PBO: 930060119

©2025  Rare Diseases South Africa NPC

Rights reserved

RDSA Privacy Policy 

Rare Diseases South Africa

NPO 120-991

The Station, 63 Peter Place, Bryanston, Sandton, 2021

(“the Organisation”)

 

MANUAL PREPARED IN ACCORDANCE WITH SECTION 51 OF THE PROMOTION OF ACCESS TO INFORMATION ACT NO. 2 OF 2000

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